Current advancements in science and technology has opened up a new era for tissue engineering which uses body’s own potential for regeneration of missing body parts. In dentistry it has led to the regeneration of missing teeth and supporting structures. Tissue engineering is a new frontier in treatment of various oral diseases proving it’s worth with each passing day.

TE uses nature as an inspiration source for the generation of extracellular matrix analogues (scaffolds), either from natural or synthetic origin as well as bioreactors and bio-devices to mimic natural physiological conditions of particular tissues. These scaffolds embed cells in a three dimensional milieu that display signals critical for the determination of cellular fate, in terms of proliferation, differentiation and migration, among others. The aim of this review is to analyze the state of the art of TE and some of its application fields.