BIOARTIFICIAL KIDNEY :

The implantable bioartificial kidney builds upon the existing extracorporeal Renal Assist Device (RAD), which is a bioartificial kidney that combines a membrane hemofilter and a bioreactor of human renal tubule cells to mimic many of the metabolic, endocrine, and immunological functions of a healthy kidney.

While clinical trials confirmed that the RAD can safely treat acute renal failure in a critical care setting, adoption of the RAD for routine treatment of ESRD patients is hampered by its labor-intensive and complex operation, large size, and high marginal cost.

The ultimate goal of the Kidney is to apply microelectromechanical systems (MEMS) and nanotechnology to miniaturize the extracorporeal RAD into a surgically implantable, self-monitoring, and self-regulating bioartificial kidney.

ARTIFICIAL EAR :

An artificial - and very lifelike - ear has been built by scientists using a 3D printer and cartilage from sheep. The organ was designed by plastic surgeons to make it look as like as possible.

AN ARTIFICIAL EAR MAY BE NEEDED DUE TO:

Congenital conditions of the ear — such as microtia

Surgery — cancer or tumour removal

Traumatic injury— traffic accidents, burn injury or other trauma

ARTIFICIAL HEART :

An artificial heart is a prosthetic device that is implanted into the body to replace the original biological heart. It is distinct from a cardiac pump, which is an external device used to provide the functions of both the heart and the lungs.

Thus, the cardiac pump need not be connected to both blood circuits.

Also, a cardiac pump is only suitable for use not longer than a few hours, while for the artificial heart the current record is 17 months.

This synthetic replacement for an organic mammalian heart (usually human), remains one of the long-sought goals of modern medicine.

Although the heart is conceptually a simple organ (basically a muscle that functions as a pump), it embodies complex subtleties that defy straightforward emulation using synthetic materials and power supplies.

ARTIFICIAL EYE : 

An artificial eye is a replacement for a natural eye lost because of injury or disease. Although the replacement cannot provide sight, it fills the cavity of the eye socket and serves as a cosmetic enhancement. Before the availability of artificial eyes, a person who lost an eye usually wore a patch. An artificial eye can be attached to muscles in the socket to provide eye movement.

BIO ARTIFICIAL LIVER :

Artificial support systems were not widely used in cases of liver failure, primarily because hepatic toxins are albumin-bound unlike for the most part uremic pollutant and hence cannot be removed by usual dialysis process.

Recently, advances have been made for the removal of hepatic toxins making it now possible to support the patient with liver failure till the liver recovers or until liver transplantation is feasible.

The major artificial liver support systems are –

1.     Peritoneal dialysis,

2.     Haemodialysis,

3.     Hemofilteration,

4.     Continuous renal replacement therapy,

5.     Charcoal Haemoperfusion,

6.     Plasma exchange,

7.     Biologic – DT sorbent System and

8.     Molecular adsorbent re circulating system.

In this method, patient's blood or plasma is pushed into bioreactors, which are empty fibre devices, seeded on the dialysate side with newly remote or cryo preserved porcine hepatocytes or changed human hepatoma cell line.

An Artificial organ is an engineered tissue that is implanted into human for interacting with living tissue to replace natural organ for the purpose of restoring a patient’s state of living back to as normal as possible. The main purpose of this process is for supporting patient’s life. The Microchip or 'organs-on-chips' provide organ function and disease, and for applications such as toxicity tests of #drug candidates.

BIO MATERIALS FOR THERAPEUTIC DELIVERY

A number of organic and inorganic, synthetic or natural derived materials have been classified as not harmful for the human body and these materials are usually named biomaterials since they are suitable for introduction into living human tissues of prosthesis, as well as for drug delivery, diagnosis, therapies, tissue regeneration and many other clinical applications. Recently, nanomaterials and bioabsorbable polymers have greatly enlarged the fields of application of biomaterials attracting much more the attention of the biomedical community.

BIO MATERIALS IN IMPLANT DESIGN

Implant Design can increase surface area of support.Design of implant has 30% to 200% greater surface area compared with a cylinder implant of the same size. 
A focus of several implant design is to reduce the plaque-related complications of treatment. It may also affect the magnitude or type of forces applied to the bone–implant interface. 

Breast Implant 

Breast Implants may be done by insertion of a silicone bag (prosthesis) under the breast (submammary) or under the breast and chest muscle (subpectoral). 

There are two types of breast implants commonly used for mammoplasty, breast reconstruction, and breast augmentation procedures: 

1. Saline implant filled with sterile saline solution.
2. Silicone implant filled with viscous silicone gel. 

Biomaterial for Orthopedic implants 

An orthopedic implant is a device surgically placed into the body designed to restore function by replacing or reinforcing a damaged structure.Orthopedic Implants & Surgical Equipment includes Bone Screws, Plates, Intramedullary Nails, Maxillofacial Implants, Knee Implants, Hip Prosthesis, Spinal Implant System, Locking Plate System, External Fixators, etc.. 

Biomaterials for Dental Implants:
Implants have been gaining popularity among the patients and frequently are being considered as a first treatment option. The goal of achieving an optimal bone-implant interface has been approached by the alteration of implant surface topography, chemistry, energy and charge as well as bulk material composition. 

Stemcells have the remarkable potential to develop into many different cell types in the body during early life & growth.When a stem cell divides, each new cell has the potential either to remain a stem cell or become another type of cell with a more specialized function, such as a muscle cell, a red blood cell, or a brain cell. It also plays an important role in Tissue Engineering for more details visit: http://bit.ly/2EgErZ2 AdvancedBiomaterials2018 June 20-21, 2018 in Rome, Italy

Why to wait???

Register now and avail early bird discounts on your registration. Advanced Biomaterials,  Tissue Engineering, Stemcells, 3DPrinting, Regenerative Medicine, Dental Implants, &  manymore

Visit : http://http://bit.ly/2EvxDa0 & http://bit.ly/2BVFQSp 

World congress on Advanced Biomaterials and Tissue Engineering brings researchers related to the field of Biomaterials, Biomedicine, Tissue Engineering, Stem cells, Artificial Organs and many more around the world to one place in Rome, Italy on June 20-21, 2018.